Leveraging our proprietary DIANA technology (DNA-linked Inhibitor Antibody Assay), we introduce the DIANA Kinase Inhibitor Profiling Panels. While DIANA Kinase panel represents the most comprehensive product, containing all available kinase assays, the focused panels, like DIANA TK Panel or DIANA CDK Panel, are preselected sets of kinase assays to address the most common customer needs. Beside all of that, our DIANA Custom Selection service represents the ultimate customization opportunity and enable our customers to fully adjust the set of kinase assays to their needs.
Download the complete DIANA Kinase Assay list here!
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Services
DIANA Kinase Panel
DIANA Kinase panel is an advanced kinase inhibitor selectivity profiling tool currently covering more than 170 kinases. Using proprietary DIANA technology it delivers quantitative affinity measurements (Kd) from single measurement.
DIANA CDK Panel
DIANA CDK panel is an advanced kinase inhibitor selectivity profiling tool which comprise 24 different CDK/cyclin complexes. Using proprietary DIANA technology it delivers quantitative affinity measurements (Kd) from single measurement.
DIANA TK Panel
DIANA TK panel is an advanced tyrosine kinase inhibitor selectivity profiling tool which comprise 68 different TKs. Using proprietary DIANA technology it delivers quantitative affinity measurements (Kd) from single measurement.
DIANA CK1 Panel
DIANA CK1 panel is an advanced CK1 (casein kinase 1) inhibitor selectivity profiling tool which comprise 7 different CK1s. Using proprietary DIANA technology it delivers quantitative affinity measurements (Kd) from single measurement.
Technology Intro
DIANA is a solid-phase competitive binding assay that uniquely combines small molecule-based DIANA probes with the strengths of ELISA and qPCR, delivering robust quantitative potency data with an exceptionally broad dynamic range. This allows researchers to obtain precise binding affinity constants (Kd) from the start of their projects at a cost comparable to conventional methods that only provide relative inhibition.
DIANA Assay
DIANA assay measures potency of tested compound as function of its competition with DIANA probe. The assay delivers true binding constants (Kd) of test compound.
DIANA Assay
The amount of displaced DIANA probe is quantitatively determined by qPCR. qPCR readout ensures high dynamic range and enables calculation of Kd from a single measurement.
DIANA Assay
Similar assay setup yields highly comparable results between the methods. Usage of recombinant kinases instead of phage constructs ensures easier kinase quality control and consistency of results.
Pricing of DIANA Kinase Panel
Product Name | Description | No. Kinases | Price per 1 compound | Turnaround Time*** | Result |
|---|---|---|---|---|---|
Panel of kinases covering entire kinome | 170* | 2500 | 14 business days | Dissociation constant (Kd) | |
Panel of tyrosine kinases (TK) | 68 | 1360 | 7 business days | Dissociation constant (Kd) | |
Panel of cyclin-dependent kinases (CDK) | 24 | 480 | 7 business days | Dissociation constant (Kd) | |
Panel of casein kinase 1 (CK1) | 7 | 140 | 7 days | Dissociation constant (Kd) | |
Custom selection | Customize kinase panel for your assay | 1 | 25** | 7 business days | Kd |
*Some kinase assays are still under validation with estimate finalization around August 2025. The current Kinase panel consists of appx. 130 kinase assays and the price for this set is 2000 EUR per compound.
**Minimal Order Quantity for Custom Selection service is 500 EUR.
***Counts from the day compounds are delivered to our testing facility. For complex orders the turnaround time can be extended to 14 business days.
Service without compromises
DIANA Assay: Accelerate Your Project and Get Quantitative Potency Data from the Start!
Quantitative potency data for the price of relative potency data
7 business days for standard and 14 business days for complex services
You can assemble your own kinase panel for comparable price as our focused panels
Our kinase assay portfolio representatively covers all kinase families within human kinome
DIANA Kinase Panel | Collaboration
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