DIANA TK Panel: Panel of 70 tyrosine kinases

(DIANA-TK-Panel)

The DIANA TK Panel is a selectivity profiling tool engineered for drug discovery, enabling precise measurement of enzyme dissociation constants (Kd) for test compounds across an extensive set of 70 Tyrosine Kinases (TKs)—covering the majority of the 90 known human TKs. Powered by our proprietary DIANA technology, this ultrasensitive panel delivers a broad dynamic range and ensures accurate Kd determination from a single measurement, streamlining the inhibitor profiling process.

Download the DIANA TK Panel Assay list here!


Download the full DIANA Kinase Inhibitor Profiling booklet here!

DIANA Technology Features

DIANA Technology: DIANA is patented solid-phase competitive binding assay that uniquely combines small molecule-based DIANA probes with the strengths of ELISA and qPCR.

Quantitative Results: Determination of quantitative potency data (Kd) from each measurement thanks to the proprietary DIANA technology.

Affordable Excellence: Our service has fast turnaround time and it is possible to fully customize the order. Finally, the pricing makes our top-tier solution accessible to everyone.

Internal Quality Control – Binding potency of known inhibitor is determined for each kinase

Service Information

Name

No. of kinases

Cpds

Price (EUR)

Turnaround time**

Result

DIANA TK Panel

70

1

1360

7 business days

Kd

Custom Selection

1

1

25*

7 business days

Kd

*Minimal Order Quantity for Custom Selection service is 500 EUR.

**Counts from the day compounds are delivered to our testing facility. For complex orders the turnaround time can be extended to 14 business days.

Prices exclude VAT

Staurosporine inhibition profile determined by DIANA TK panel compared with reference data

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DIANA is a solid-phase competitive binding assay that uniquely combines small molecule-based DIANA probes with the strengths of ELISA and qPCR, delivering robust quantitative potency data with an exceptionally broad dynamic range. This allows researchers to obtain precise binding affinity constants (Kd) from the start of their projects at a cost comparable to conventional methods that only provide relative inhibition.

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DIANA TK Panel | Collaboration

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