(DIANA-TK-Panel)
The DIANA TK Panel is a state-of-the-art selectivity profiling tool engineered for drug discovery, enabling precise measurement of enzyme dissociation constants (Kd) for test compounds across an extensive set of 68 Tyrosine Kinases (TKs)—covering the majority of the 90 known human TKs. Powered by our proprietary DIANA technology, this ultrasensitive panel delivers a broad dynamic range and ensures accurate Kd determination from a single measurement, streamlining the inhibitor profiling process.
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DIANA Technology Features
DIANA Technology: DIANA is patented solid-phase competitive binding assay that uniquely combines small molecule-based DIANA probes with the strengths of ELISA and qPCR.
Quantitative Results: Determination of quantitative potency data (Kd) from each measurement thanks to the proprietary DIANA technology.
Affordable Excellence: Our service has fast turnaround time and it is possible to fully customize the order. Finally, the pricing makes our top-tier solution accessible to everyone.
Internal Quality Control – Binding potency of known inhibitor is determined for each kinase
Service Information
Name | No. of kinases | Cpds | Price (EUR) | Turnaround time** | Result |
|---|---|---|---|---|---|
DIANA TK Panel | 68 | 1 | 1360 | 7 business days | Kd |
Custom Selection | 1 | 1 | 25* | 7 business days | Kd |
*Minimal Order Quantity for Custom Selection service is 500 EUR.
**Counts from the day compounds are delivered to our testing facility. For complex orders the turnaround time can be extended to 14 business days.
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DIANA is a solid-phase competitive binding assay that uniquely combines small molecule-based DIANA probes with the strengths of ELISA and qPCR, delivering robust quantitative potency data with an exceptionally broad dynamic range. This allows researchers to obtain precise binding affinity constants (Kd) from the start of their projects at a cost comparable to conventional methods that only provide relative inhibition.
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DIANA CDK Panel | Collaboration
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