(DIANA-CDK-Panel)
The DIANA CDK Panel is an advanced selectivity profiling tool designed for drug discovery, enabling the precise measurement of enzyme dissociation constants (Kd) for target compounds against a comprehensive set of 24 Cyclin Dependent Kinases (CDKs). Utilizing our proprietary DIANA assay, this ultrasensitive panel offers a wide dynamic range, ensuring reliable Kd determination from a single well in a multi-well plate format.
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DIANA Technology Features
DIANA Technology: DIANA is patented solid-phase competitive binding assay that uniquely combines small molecule-based DIANA probes with the strengths of ELISA and qPCR.
Quantitative Results: Determination of quantitative potency data (Kd) from each measurement thanks to the proprietary DIANA technology.
Affordable Excellence: Our service has fast turnaround time and it is possible to fully customize the order. Finally, the pricing makes our top-tier solution accessible to everyone.
Internal Quality Control – Binding potency of known inhibitor is determined for each kinase
Service Information
Name | No. of kinases | Cpds | Price (EUR) | Turnaround time** | Result |
|---|---|---|---|---|---|
DIANA CDK Panel | 24 | 1 | 480 | 7 business days | Kd |
Custom Selection | 1 | 1 | 25* | 7 business days | Kd |
*Minimal Order Quantity for Custom Selection service is 500 EUR.
**Counts from the day compounds are delivered to our testing facility. For complex orders the turnaround time can be extended to 14 business days.
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Inhibitor Profiling: Kinases
DIANA is a solid-phase competitive binding assay that uniquely combines small molecule-based DIANA probes with the strengths of ELISA and qPCR, delivering robust quantitative potency data with an exceptionally broad dynamic range. This allows researchers to obtain precise binding affinity constants (Kd) from the start of their projects at a cost comparable to conventional methods that only provide relative inhibition.
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DIANA CDK Panel | Collaboration
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