DIANA CDK Panel: The Only Complete Set of All CDKs for Inhibitor Profiling

(DIANA-CDK-Panel)

The DIANA CDK Panel is an advanced selectivity profiling platform designed for drug discovery, enabling precise determination of dissociation constants (Kd) for inhibitor compounds across the complete set of all 20 Cyclin Dependent Kinases (CDKs). In addition, for several CDKs we provide multiple physiologically relevant cyclin bound variants, resulting in a uniquely comprehensive collection of 24 CDK/cyclin complexes.


This full family coverage is unmatched. DIANA Biotechnologies is the only provider offering all 20 CDKs for inhibitor profiling. Powered by our proprietary ultrasensitive DIANA assay, the panel ensures a wide dynamic range and reliable single well Kd quantification to support confident decision making in kinase inhibitor development


Download the full DIANA Kinase Inhibitor Profiling booklet here!

DIANA Technology Features

DIANA Technology: DIANA is patented solid-phase competitive binding assay that uniquely combines small molecule-based DIANA probes with the strengths of ELISA and qPCR.

Quantitative Results: Determination of quantitative potency data (Kd) from each measurement thanks to the proprietary DIANA technology.

Affordable Excellence: Our service has fast turnaround time and it is possible to fully customize the order. Finally, the pricing makes our top-tier solution accessible to everyone.

Internal Quality Control – Binding potency of known inhibitor is determined for each kinase

Service Information

Name

No. of kinases

Cpds

Price (EUR)

Turnaround time**

Result

DIANA CDK Panel

24

1

480

7 business days

Kd

Custom Selection

1

1

25*

7 business days

Kd

*Minimal Order Quantity for Custom Selection service is 500 EUR.

**Counts from the day compounds are delivered to our testing facility. For complex orders the turnaround time can be extended to 14 business days.

Prices exclude VAT

Comparative analysis of inhibition profile of Staurosporine

Axis decription:x: Kd (nM); log scale; y: Cpd concentration (nM); log scale. The CDK20 used in the CDK panel is a murine protein that is 94% identical to human CDK20. All the other CDKs are human

Profiling of selected kinase inhibitors by DIANA CDK panel (Kd)

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DIANA CDK Panel | Collaboration

Interested in inhibitor profiling using DIANA CDK Panel? Send us a message!