Introducing the DIANA Kinase Panel for kinase inhibitor profiling. Leveraging our proprietary DIANA technology (DNA-linked Inhibitor Antibody Assay), this panel offers high sensitivity and dynamic range, allowing for the precise determination of enzyme dissociation constants (Kd) from a single well. With minimal reaction volumes and efficient use of antibodies, antigens, and inhibitors, our multi-well plate format supports high-throughput kinase screening, making it an indispensable asset for your research.
The DIANA Kinase Panel screens more than 170 clinically relevant kinases across all major families, with continuous expansion to include complete subsets, such as the newly available DIANA CDK Panel. As kinases are pivotal in numerous cellular processes and disease mechanisms, our kinase screening panel is essential for drug discovery, providing reliable, literature-aligned inhibitor profiles that underscore the robustness and sensitivity of DIANA technology.
Would you like to see the full DIANA Kinase Pane leaflet? Download it here!
DIANA is a multi-well plate assay, where target protein is selectively captured to the solid carrier and then bound by a unique detection probe consisting of a small-molecule ligand linked to a DNA-oligonucleotide. Subsequently, the probe is detected and quantified by qPCR. For drug discovery, the assay utilizes competition between the probe and the test compounds to measure their binding affinity. DIANA is straightforward to develop for new targets and easy to implement using standard laboratory equipment.
DIANA Kinase Panel, which currently enables rapid potency and selectivity profiling of target compounds against approximately 170 kinases, representing clinically relevant kinases from all kinase families (AGC, CAMK, CK1, CMGC, STE, TK, TKL).
The gradual panel expansion is introducing the complete subsets corresponding to specific kinase families. As an example, the first complete DIANA CDK Panel is available for small molecules profiling.
Download the complete list of Kinases!
Document name | Download |
|---|---|
DIANA Kinase Panel: List of kinases | Download |
Pricing of DIANA Kinase Panel
Product Name | No. Kinases | No. Cpds | Price | Turnaround Time | Result |
|---|---|---|---|---|---|
DIANA Kinase Panel | 170* | 1 | 2500 EUR | 14 business days** | Dissociation constant (Kd) |
*Some kinase assays are still under validation with estimate finalization around August 2025. The current Kinase panel consists of 130 kinase assays and the price for this set is 2000 EUR per compound.
**Counts from the day compounds are delivered to our testing facility. For complex orders the turnaround time can be extended to 14 business days.
DIANA Kinase Panel | Collaboration
Write us